1,077 research outputs found

    BANet: Blur-aware Attention Networks for Dynamic Scene Deblurring

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    Image motion blur usually results from moving objects or camera shakes. Such blur is generally directional and non-uniform. Previous research efforts attempt to solve non-uniform blur by using self-recurrent multi-scale or multi-patch architectures accompanying with self-attention. However, using self-recurrent frameworks typically leads to a longer inference time, while inter-pixel or inter-channel self-attention may cause excessive memory usage. This paper proposes blur-aware attention networks (BANet) that accomplish accurate and efficient deblurring via a single forward pass. Our BANet utilizes region-based self-attention with multi-kernel strip pooling to disentangle blur patterns of different degrees and with cascaded parallel dilated convolution to aggregate multi-scale content features. Extensive experimental results on the GoPro and HIDE benchmarks demonstrate that the proposed BANet performs favorably against the state-of-the-art in blurred image restoration and can provide deblurred results in real-time

    Role of antisense RNAs in evolution of yeast regulatory complexity

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    AbstractAntisense RNAs (asRNAs) are known to regulate gene expression. However, a genome-wide mechanism of asRNA regulation is unclear, and there is no good explanation why partial asRNAs are not functional. To explore its regulatory role, we investigated asRNAs using an evolutionary approach, as genome-wide experimental data are limited. We found that the percentage of genes coupling with asRNAs in Saccharomyces cerevisiae is negatively associated with regulatory complexity and evolutionary age. Nevertheless, asRNAs evolve more slowly when their sense genes are under more complex regulation. Older genes coupling with asRNAs are more likely to demonstrate inverse expression, reflecting the role of these asRNAs as repressors. Our analyses provide novel evidence, suggesting a minor contribution of asRNAs in developing regulatory complexity. Although our results support the leaky hypothesis for asRNA transcription, our evidence also suggests that partial asRNAs may have evolved as repressors. Our study deepens the understanding of asRNA regulatory evolution

    EFFECT OF DIFFERENT RUNNING SPEED ON VERTICAL OSCILLATION AND STRIDE

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    The main purpose of this study was to investigate the effect of different running speed (3.5±O.3 and 4.9±O.2 m/si on vertical oscillation of the center of gravity and stride. Ten male elite running players served as subjects. A camera (60Hz) was to collect the parameters during running. From this research, the t-Test is used to analyze the parameters of the kinematics in different running speed. Results indicated that different running speed would not affect the vertical oscillation of human body center of gravity. In addition, a significant difference (p< .05) was found in the same speed of different step, but no significance was found in different running speed of the same step. The duration of the stance phase in lower speed for about 38.34% of the stride and the swing phase for 61.66%, in higher speed for about 32.11 % and 67.89%

    Signatures of afterglows from light dark matter boosted by supernova neutrinos in current and future large underground detectors

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    Supernova neutrino boosted dark matter (SNν\nu BDM) and its afterglow effect have been shown to be a promising signature for beyond Standard Model (bSM) physics. The time-evolution feature of SNν\nu BDM allows for possibly direct inference of DM mass mχm_\chi, and results in significant background suppression with improving sensitivity. This paper extends the earlier study and provides a general framework for computing the SNν\nu BDM fluxes for a supernova that occurs at any location in our galaxy. A bSM U(1)LμLτU(1)_{L_\mu-L_\tau} model with its gauge boson coupling to both DM and the second and third generation of leptons is considered, which allows for both DM-ν\nu and DM-ee interactions. Detailed analysis of the temporal profile, angular distribution, and energy spectrum of the SNν\nu BDM are performed. Unique signatures in SNν\nu BDM allowing extraction of mχm_\chi and detail features that contain information of the underlying interaction type are discussed. Expected sensitivities on the above new physics model from Super-Kamiokande, Hyper-Kamiokande, and DUNE detections of BDM events induced by the next galactic SN are derived and compared with the existing bounds.Comment: 17 pages, 15 figures, 1 table, 5 appendice

    Alleviating Interference through Cognitive Radio for LTE-Advanced Network

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    In the LTE-Advanced network, some femtocells are deployed within a macroecell for improving throughput of indoor user equipments (UEs), which are referred to as femtocell UEs (FUEs). Cross-tier interference is an important issue in this deployment, which may significantly impact signal quality between Macrocell Base Stations (MBSs) and Macrocell User Equipments (MUEs), especially for MUEs near the femtocell. To relieve this problem, the Third Generation Partnership Project Long Term Evolution-Advanced (3GPP LTE-Advanced) de fined the cognitive radio enhanced femtocell to coordinate interference for LTE-Advanced Network. Cognitive radio femtocells have the ability to sense radio environment to obtain radio parameters. In this paper, we investigated the performance of existing schemes based on fractional frequency reuse. Therefore, we proposed a scheme with cognitive radio technology to improve the performance of fractional fre-quency reuse scheme. Simulation results showed that our scheme can effectively enhance average downlink throughput of FUEs as well as the total downlink throughput in LTE-Advanced Networks

    Influence of electrode thermal conductivity on resistive switching behavior during reset process

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    Resistive random access memory (RRAM) is the most promising candidate for non-volatile memory (NVM) due to its extremely low operation voltage, extremely fast write/erase speed, and excellent scaling capability. However, an obstacle hindering mass production of RRAM is the non-uniform physical mechanism in its resistance switching process. This study examines the influence of different electrode thermal conductivity on switching behavior during the reset process. Electrical analysis methods and an analysis of current conduction mechanism indicate that better thermal conductivity in the electrode will require larger input power in order to induce more active oxygen ions to take part in the reset process. More active oxygen ions cause a more complete reaction during the reset process, and cause the effective switching gap (dsw) to become thicker. The effect of the electrode thermal conductivity and input power are explained by our model and clarified by electrical analysis methods. Please click Additional Files below to see the full abstract

    Human parvovirus B19 nonstructural protein NS1 enhanced the expression of cleavage of 70 kDa U1-snRNP autoantigen

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    <p>Abstract</p> <p>Background</p> <p>Human parvovirus B19 (B19) is known to induce apoptosis that has been associated with a variety of autoimmune disorders. Although we have previously reported that B19 non-structural protein (NS1) induces mitochondrial-dependent apoptosis in COS-7 cells, the precise mechanism of B19-NS1 in developing autoimmunity is still obscure.</p> <p>Methods</p> <p>To further examine the effect of B19-NS1 in presence of autoantigens, COS-7 cells were transfected with pEGFP, pEGFP-B19-NS1 and pEGFP-NS1K334E, a mutant form of B19-NS1, and detected the expressions of autoantigens by various autoantibodies against Sm, U1 small nuclear ribonucleoprotein (U1-snRNP), SSA/Ro, SSB/La, Scl-70, Jo-1, Ku, and centromere protein (CENP) A/B by using Immunoblotting.</p> <p>Results</p> <p>Significantly increased apoptosis was detected in COS-7 cells transfected with pEGFP-B19-NS1 compared to those transfected with pEGFP. Meanwhile, the apoptotic 70 kDa U1-snRNP protein in COS-7 cells transfected with pEGFP-B19-NS1 is cleaved by caspase-3 and converted into a specific 40 kDa product, which were recognized by anti-U1-snRNP autoantibody. In contrast, significantly decreased apoptosis and cleaved 40 kDa product were observed in COS-7 cells transfected with pEGFP-NS1K334E compared to those transfected with pEGFP-B19-NS1.</p> <p>Conclusions</p> <p>These findings suggested crucial association of B19-NS1 in development of autoimmunity by inducing apoptosis and specific cleavage of 70 kDa U1-snRNP.</p

    Chinese Herbal Medicine Therapy and the Risk of Mortality for Chronic Hepatitis B Patients with Concurrent Liver Cirrhosis: a Nationwide Population-Based Cohort Study

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    Chronic hepatitis B (CHB) is increasingly recognized as a public health problem in Taiwan. After affected patients are diagnosed with contaminant liver cirrhosis (LC), adverse clinical outcomes, especially death, are common. This study aimed to investigate the effect of Chinese herbal medicine (CHM), an essential branch of Traditional Chinese medicine (TCM), on the mortality risk among CHB patients with contaminant LC. This longitudinal cohort study used the Taiwanese National Health Insurance Research Database to identify 1522 patients 20–70 years of age with newly diagnosed CHB with LC during 1998–2007. Among them, 508 (33.37%) had received CHM products after the onset of CHB (CHM users), and the remaining 1014 patients (66.63%) were designated as a control group (non-CHM users). All enrollees were followed until the end of 2012 to determine deaths during the study period. We applied the Cox proportional hazards regression model to compute the hazard ratio for the association of CHM use and the subsequent risk of death. During the follow-up period, 156 CHM users and 493 non-CHM users died. After controlling for potential confounders, CHM users were found to have a significantly reduced risk of death compared with non-CHM users by 56%, and the effect was predominantly observed among those treated with CHM for \u3e 180 days. CHM therapy lowered the risk of death among CHB patients with contaminant LC, which supported CHM might provide further treatment options for those with chronic liver diseases
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